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conclusions

1. Clinical features atrophic Helicobacter pylori assotsiirovannogo a gastritis at elderly and senile age are high frequency of occurrence of symptoms of a gastric dyspepsia,

And also more expressed, than at persons young and middle age endoscopic signs of an atrophy of a mucosa of a stomach.

2. Morphological signs atrophic Helicobacter pylori assotsiirovannogo a gastritis at sick senior age groups,

In comparison with persons young and middle age are characterised by more essential processes of an atrophy and an intestinal metaplasia, and also depression of total and functional activity of neuroendocrinal cells of a mucosa of a stomach. The specified morphological disturbances have pathogenetic communication with duration persistirovanija Helicobacter pylori in a stomach mucosa.

3. Involutional processes of a mucosa of a stomach at persons of elderly and senile age are characterised by oppression of proliferative cellular activity and apoptosis intensifying that is shown by disturbance of resistance and regeneratornoj abilities of cells of a mucosa of a stomach, and also disorder of structurally - functional organisation of neuroendocrinal cells. At elderly and senile age involutional changes of a mucosa of a stomach are the burdening factor of a current atrophic Helicobacter pylori assotsiirovannogo a gastritis.

4. Peptidnyj a bioregulator dipeptide lizil-glutaminovaja acid strengthens proliferative potential of cells of a mucosa of a stomach, stimulating with that neogenesis at atrophic Helicobacter pylori assotsiirovannom a gastritis at persons of the senior age group. Dipeptide lizil-glutaminovaja acid raises total and functional activity of neuroendocrinal cells of a mucosa of a stomach, providing normalisation of the broken structurally functional organisation of the neuroendocrinal cells, caused by ageing and atrophic Helicobacter pylori assotsiirovannym a gastritis.

5. Dipeptide lizil-glutaminovaja acid reduces degree of inflammatory cellular infiltration of a mucosa of a stomach at atrophic Helicobacter pylori assotsiirovannom a gastritis at persons elderly and starcheskoju age, framing favorable conditions for cupping of relapse of disease.

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A source: ANTSIFEROV Roman Vladimirovich. CLINICO-MORPHOLOGICAL FEATURES of the CURRENT of the ATROPHIC GASTRITIS At PERSONS of the SENIOR AGE GROUPS. The DISSERTATION on competition of a scientific degree of the candidate of medical sciences. St.-Petersburg - 2007. 2007

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