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proliferativnajaactivity EK of an aorta of the person in culture

Relative analysis proliferativnoj activity EK in the cultures received from visually "normal" and atherosclerotic aortas in comparable age-grades, has revealed considerable decrease rostovyh parametres of cages in the latter case.

So, at use of density of alighting of an order of 2-2 cages/sm2 in the environment of growth without additional rostovyh factors only EK from normal pots possessed ability awakely proliferirovat and to reach states konfljuentnogo a monolayer. Formation of intercellular contacts was accompanied by a contact inhibition that showed in the form of incorporation decrease mechenogo the predecessor of synthesis of DNA - [3Н] a-thymidine. On the contrary, growth rate EK from atherosclerotic pots was low, and such cultures to a monolayer state, as a rule, did not grow. In a stage of awake growth timidinovyj an index of cultures (% EK containing mechenye

G

Kernels) has compounded 9.3+1.8 % for normal and 3.6+2.2 % for atherosclerotic aortas, accordingly (reliability of distinctions, r

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A source: ROMANOV Jury Askoldovich. STRUCTURALLY FUNCTIONAL FEATURES ENDOTELIJA of the PERSON In NORM And AT the ATHEROSCLEROSIS. The dissertation on competition of a scientific degree of a Dr.Sci.Biol. Moscow - 2003. 2003

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