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2.2.1 Choice and the maintenance of laboratory animals

Experimental researches are executed on 680 white not purebred rats-males in mass 180-220 g, 520 white not purebred

Mice-males and 140 mice-males of line BALB/c in mass 18-20 g distributings of nursery of laboratory animals "Rappolovo" (Rappolovo the Leningrad region)

The choice of animals for experiments was defined by that rats and mice are standard object in biological researches, possess comparable to other kinds of laboratory animals and the person sensitivity to radiation action, tsitostatikov and viruses, are recommended as object of research for doklinicheskoj estimations of pharmacological agents [103, 104].

Animals contained in standard conditions of a vivarium, in the conditions of inverted light with 8 to 20 ch at temperature (22 yo 2) 0С, no more than on 6 rats or on 10 mice in one cell. Feeding of animals carried out once a day in first half of day, access of animals to the standard granulated forage and water was not limited (a diet - ad libitum). Before carrying out of each experiment animals were under observation (in quarantine) during not less than 14 days After the termination of quarantine of mice distributed on groups a method of the randomization, the sick and weakened animals in experimental researches did not include.

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A source: JARTSEVA Anna Aleksandrovna. PATHOPHYSIOLOGICAL BASES of APPLICATION of DISULPHIDES GLUTATIONA As AGENTS of PREVENTIVE MAINTENANCE And TREATMENT HIMIOLUCHEVYH ORAL MUKOZITOV At SICK of CANCER OROFARINGEALNOJ of AREA (clinico-experimental research). The dissertation on competition of a scientific degree of the doctor of medical sciences. St.-Petersburg. 0000

More on topic 2.2.1 Choice and the maintenance of laboratory animals:

  1. Chapter 3. The EXPERIMENTAL ESTIMATION of the BASIC LINKS of PATHOGENESIS HIMIOLUCHEVYH ORAL MUKOZITOV AT THEIR MODELLING ON FINE LABORATORY ANIMALS
  2. 2.4 Choice of formulas of reagents and laboratory researches of efficiency of influence on productive layers
  3. maintenance of a choice quality of personnel potential
  4. 2.2.4. Studying of conditions of maintenance and storage of cultures M pachydermatis in laboratory conditions
  5. the Maintenance of sexual hormones in blood serum of animals with models of functional cysts and their treatment by monopolar coagulation
  6. § 3. Legality maintenance at a choice of a kind and the size of administrative punishment as a way of protection of the rights of citizens
  7. § 2. Freedom of the educational organisations in a choice of uchebno-methodical maintenance and educational technologies
  8. 2.2. Animals and tumoral model
  9. 2.1.1. Animals.
  10. comparison of results of laboratory and numerical experiments