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INTRODUCTION

Urgency of a theme of research

The lung cancer is one of the most widespread malignant tumours in the world, keeping "in the lead" positions in structure of a case rate among oncologic patients (Bisenkov L.N., 2006; barin's son A.S., 2009; Jemal A., et al., 2010; Reinmuth N., 2013).

In 2010 in the Russian Federation 516874 new cases of malignant neoplasms, from which 56985 (11,02 %) have been diagnosed

It was necessary on a lung cancer. Among the man's population of the Russian Federation the lung cancer wins first place in structure of a case rate - 46407 cases (19,5 %), and among the female population - 10 place - 10578 cases (3,8 %). The case rate structure malignant neoplasms of men at the age of 30-59 years essentially differs from that at women of the same age. At men neoplasms of a trachea, bronchuses and easy (20,9 %) (Chissov V. I and co-workers dominate., 2012).

Despite the reached progress at the expense of introduction and perfection of new methods of radial, endoscopic and pathomorphologic diagnostics, results of treatment sick of a lung cancer remain unfavourable (Barin's son A.S. And co-workers., 2009; Davidov M. I, 2009).

There is opened a question on diagnostics of a cancer of a lung with secondary inflammatory and is purulent-destructive changes in a pulmonary parenchyma and a thoracal cavity (Bisenkov L.N., 2006; Yablonsky P. K, 2010). Special value gives to this problem that fact, that patients with such forms of disease with the account of a clinical picture and results of radial diagnostics are originally hospitalised in hospitals of the general profile (Smiths I.M., 2005).

At the majority of patients with the complicated current of a cancer of a lung infectious complications, instead of prevalence of tumoral process, are the lethality reason (Pavlushkov E.N., 2007).

Degree of a readiness of a theme.

The current of a cancer of a lung quite often becomes complicated development of secondary inflammatory process. According to different authors, the share of the complicated forms of a cancer of a lung makes from 13,7 to 51,4 % (Smiths I.M., 2005; Bisenkov L.N., 2006; Pavlushkov E.N., 2007; Yablonsky P. K, 2010; Karakelides H., 2003; Kumar K.G., 2004).

Joining of a secondary bacteriemic infection to tumoral process is shown by the features of a clinical picture essentially complicating timely and exact diagnostics of a cancer easy (Trahtenberg A.H., 2009). Thus in a clinical picture of disease on the foreground there are the symptoms inherent to nonspecific inflammatory diseases of lungs (Chang J.Y., 2012).

Application of a traditional radiological method of diagnostics not to the full meets modern demands to a preoperative estimation of tumoral process at sick of a cancer easy (Bukovskaja J.V., 2003; Goitein O., 2008).

The x-ray computer tomography keeps now "in the lead" positions among methods of radial diagnostics of a cancer easy (Tjurin I.E. 2003, 2008; Trufanov G. E, 2011). However, at development of secondary inflammatory processes in a pulmonary parenchyma surrounding a tumour there are problems of a differentiation of borders of a tumour at carrying out of a computer tomography (Rami-Porta R., 2007).

In comparison with a computer tomography the magnitno-resonant tomography rather has entered recently into practice of radial researches of organs of a breast and especially easy (Gamova E.V., 2006; Laurent F., 2006; Regier M., 2007; Kauczor H-U., 2009).

At the same time, known advantages of a method in visualisation of various organs and tissues with high fabric contrast have put it abreast perspective methods of research of lungs. However, the works devoted to the analysis of possibilities of a magnitno-resonant tomography in diagnostics of complicated forms of a cancer of a lung a few, and the data stated in them, have inconsistent character.

There is not resolved a question on a technique, possibilities and efficiency of a magnitno-resonant tomography in diagnostics of a cancer of the lung complicated by secondary inflammatory changes. Indications are not developed for carrying out of a magnitno-resonant tomography at a lung cancer, including, accompanied by secondary inflammatory changes in a pulmonary parenchyma (Frolova I.G., 2010; Bruzzi J.F., 2008).

All it causes an urgency and necessity of the present research.

Research objective. Improvement of radial diagnostics of a cancer of a lung with the complicated current on the basis of application x-ray computer and vysokopolnoj magnitno-resonant tomographies.

Research problems:

1. To define possibilities of a x-ray computer tomography in the characteristic of tumoral knot, local prevalence and a lesion regionarnyh lymph nodes at an uncomplicated current of a cancer of a lung.

2. To improve a technique vysokopolnoj a magnitno-resonant tomography of a breast at patients with the complicated current of a cancer of a lung.

3. To define a role and possibilities of a x-ray computer and magnitno-resonant tomography in an estimation local and regionarnoj prevalence of tumoral process at the complicated current of a cancer of a lung.

4. To define indications for carrying out of a magnitno-resonant tomography at sick of a lung cancer.

Scientific novelty of research.

Possibilities of a computer tomography in visualisation of borders of tumoral knot, an estimation local and regionarnogo diffusions are limited, owing to impossibility of a differentiation of tumoral process and secondary inflammatory changes. The estimation of local diffusion of a cancer of a lung at the complicated current not always is correct according to a computer tomography.

It is proved, that the magnitno-resonant tomography is a specifying method in diagnostics and the tumour characteristic at the complicated current of a cancer of a lung and in most cases surpasses results of a computer tomography in an estimation of the true sizes of tumoral knot and degree local and regionarnogo diffusions.

The technique vysokopolnoj a magnitno-resonant tomography of the breast, meaning a choice of optimum planes of scanning depending on results of a previous computer tomography is fulfilled.

Indications for carrying out of a magnitno-resonant tomography at patients with the complicated current of a cancer of a lung are defined.

Radial inspection sick of a cancer of a lung with the complicated current of tumoral process is expedient to supplement with carrying out magnitnorezonansnoj tomographies with reception of an electrocardiogram-synchronised and postcontrast Т1-ВИ with a technique zhiropodavlenija.

The theoretical and practical importance.

For the first time possibilities of computer and magnitno-resonant tomographies in a preoperative estimation are analysed and generalised

Prevalence of tumoral process in comparison with morphological research at the cancer of a lung complicated by secondary inflammatory process.

It is systematised and specified it is computer-tomograficheskaja a semeiology of the uncomplicated and complicated forms of a cancer of a lung.

The sequence of application of computer and magnitno-resonant tomographies in a preoperative estimation is scientifically proved

Prevalence of tumoral process at patients with the complicated current of a cancer of a lung.

Diagnostic value of a magnitno-resonant tomography in an estimation local and regionarnoj prevalence of a cancer of a lung is defined at its complicated current. At comparison of data of a magnitno-resonant tomography and pathomorphologic research in definition of a stage of tumoral process by criterion T high force of correlation between studied variables (factor of correlation 0,93 is defined, at p

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A source: GRISHCHENKOV Alexander Sergeevich. COMPUTER And MAGNITNO-RESONANT TOMOGRAPHIES In DIAGNOSTICS of the CANCER of the LUNG COMPLICATED by SECONDARY INFLAMMATORY PROCESS the Dissertation on competition of a scientific degree of the candidate of medical sciences. St.-Petersburg. 2014

More on topic INTRODUCTION:

  1. in introduction
  2. INTRODUCTION
  3. INTRODUCTION
  4. 10.1. Introduction
  5. INTRODUCTION
  6. approbation and introduction of results.
  7. Introduction
  8. Introduction
  9. INTRODUCTION
  10. INTRODUCTION
  11. Introduction
  12. Introduction