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CHAPTER 6. DISCUSSION OF RESULTS OF OWN RESEARCHES AND THE CONCLUSION

Morphological research gastrobioptatov at chronic Nr-assotsiirovannom a gastritis is basic in a diagnosis establishment (Remmele W., 1984) and the further definition of tactics of conducting patients with gastroduodenalnoj a pathology.

Despite wide application, to these holes possibilities of a cytologic method in diagnostics of a chronic gastritis, assotsiirovannogo with Helicobacter pylori are not defined.

Proceeding from tasks in view, by us were spent relative morphological (histological and cytologic) researches for revealing of cytologic signs chronic Helicobacter ru§og_ - assotsiirovannogo a gastritis, established by a visually-analogue scale of the Sydney system (1994): defined criteria akgivnosti and expressivenesses of inflammatory reaction, epithelium transformation to a course gastriticheskogo process on cytologic Unguentums-prints, and also interrelation of these signs with colonisation Nr.

Researches spent to some stages because of impossibility of one-stage reception of serial cytologic preparations. The choice of a mean of preparation of cytologic preparations has been defined after relative analysis of several procedures. Comparison of results of histological and cytologic researches gastrobioptatov at chronic Nr-assotsiirovannom a gastritis has shown their comparability on exhibiting of activity and expressiveness of an inflammation, bacterial obsemenennosti and to presence intestinal metaplazii. This position has appeared applicable only to a findings of investigation of traditional Unguentums-prints with gastrobioptatov.

Comparison of efficacyy of procedures of preparation of monolayer cytologic Unguentums has shown, that «Cytospin»-npenapaTbi have revealed in
Whole higher percent informativnosti - 59,26 %, whereas «CellPrint» only 29,63 %. Sensitivity in definition of signs intestinal metaplazii on «Cytospin»-npenapaTaM has compounded 62,5 %, on «СеІ1Ргіт» to-preparations only in 43,8 %, at authentic presence of this sign in traditional Unguentums-prints. The monolayer preparations prepared with the help «Cytospin» and «CellPrint», have appeared suitable only for quality standard of separate signs of a chronic gastritis - its activity and metaplazii an epithelium. It has appeared more expedient nrshchhgavlivag some Unguentums-prints with gastrobioptata, it and had been made preference.

In bunch of 224 patients the chronic gastritis met in a wide age range from 18 till 70 years, among surveyed men but to comparison with women 1,24:1 slightly prevailed. The greatest quantity of patients HG were in the senior age categories, 30,36 % had age is more senior 60 years. Studying analysis atroficheskih changes SOZH on gastrobioptatam at 224 patients HG has shown the greatest rate of their development in the age season from 31 till 40 years. Stable progressing, the atrophy of epithelium SOZH reaches 94,12 % in an age-grade is more senior 60 years. The obtained data will be co-ordinated with opinion of explorers that infitsirovanie helikobakterijami descends mainly at children's age (Novikova L.D., 2002; Lapina T.V., 1999), and, depending on

Their duration persistentsii, there is a progressing morfoyofunktsionalnyh changes in SOZH (Sipponen P, and soavt., 1999; Aruin L.I. and soavt., 1998; Rowland M, 1999).

Results of researches gastrobioptatov from 224 patients the expressed direct correlation dependence between activity HG and obsemenennostju Nr (r

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A source: Beljaeva Olga Pavlovna. CYTOLOGIC And HISTOLOGICAL COMPARISONS AT MORPHOLOGICAL DIAGNOSTICS of the CHRONIC GASTRITIS, ASSOTSIIROVANNOGO With HELICOBACTER PYLORI the DISSERTATION on competition of a scientific degree of the candidate of medical sciences. Chelyabinsk -. 2006

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