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2.6. Action mastometrina on an organism of sows at preventive maintenance and treatment of postnatal diseases

At akushersko-gynecologic diseases timely preventive actions which promote fast recover and restoration of reproductive function of an animal have crucial importance.

In svinovodstve preventive maintenance of gynecologic diseases spend antibiotics, hormones, chemotherapeutic preparations which lead to time enriching of a state of health of an animal, and, as a rule, sharp pathologies take the form of chronic diseases.

It is known, that diseases of sexual system in a puerperal period make negative impact on reproductive function of sows and increase percent of  destruction of pigs.

The purpose of our work was studying of influence Mastometrina (the sire of Open Company "Хелвет", Moscow) on a postnatal pathology at sows. The Mastometrin-veterinary complex homoeopathic preparation possessing directed anti-inflammatory action on reproductive members of females and regulating their function.

Mastometrin it is used as preventive and medical means at sharp and chronic inflammatory processes of a various aetiology in a uterus, a neck to a uterus and in a vagina at cows, dogs, cats (V.V. Davydsnkov, 2003).

Mastometrin состоігг from three components, each of which has wide application in homoeopathic practice: Lachcsis, Pulsatilla, Sabina, Sepia, and as widely known preparation АСД-2 in gomeopatizirovannom a kind.

Researches spent on two bunches of animals: skilled and control. In skilled bunch to sows (17 animals) introduced a preparation "Mastometrin" intramuscularly in a dose of 5 ml once a day within three days (for 1,4, 8 day) after oporosa, in control bunch to sows (17 animals) introduced a preparation "Oksitotsin" (the economy scheme) intramuscularly in a dose 25 units, 2 times in day three days after oporosa. Before introduction of preparations for 10 day studied morphological, biochemical, immunologicheskie indicators of blood and histological researches of reproductive members.

After introduction oksitotsina to sows after sorts the clinical picture sharp postnatal endometrita has shown for 4 day at 30 % of animals and was present to. 10th day inclusive. Observed appetite decrease, abundant abjections from outside generative organs mucous or mucopurulent ekssudata which quantity increased after lying of an animal.

In control bunch of sows for 10 day after introduction oksitotsina in blood statistically doubtful augmentation of erythrocytes, in the leukocytic formula papochkojadernyh neutrophils, but statistically doubtful reduction SOE, leucocytes, haemoglobin, in the leukocytic formula segmentojadernyh neutrophils was marked. Statistically authentic augmentation in the leukocytic formula of eosinocytes with 11,21 ±0,33 to 11,31 ±0,01 %, segmentojadernyh neutrophils with 29,21 ±1,12 to 33,03±1,14 %, but reduction of lymphocytes with 49,56±0,01 to 49,01 ±0,06 %, monotsitov with 6,41±0,44 TO 3,41±0,34 % (tab. 2.6.1).

In skilled bunch of sows, at studying of therapeutic efficacyy mastometrina, it has been established, that next day after the first introduction of a preparation 17 sows (73 %) had clinical signs endometrita. Observed abundant liquid mucous, or mucopurulent abjections, at two sows they were purulent character with a blood admixing, however after the second introduction for 7 day after sorts clinical recover of animals.

Table 2.6.1.

In a puerperal period

Indicators Bunches of animals
Before introduction After introduction
The control The skilled The control The skilled
SOE mm/ch 11,8110,44 11,2710,74 11,5310,36 9,3710,14*
Erythrocytes, Х10,2 5,4010,87 4,2110,66 6,4410,56 6,5010,24*
Leucocytes, Х109 17,52±0,46 17,3210,95 17,12±0,45 11,6411,36*
Haemoglobin, g / % 10,4210,24 G 10,3310,23 10,1710,13 11,8710,44 »
Eosinocytes, % 11,21±0,03 11,8410,22 11,3110,01* 11,2310,26
Neutrophils, % Juvenile

Palochkojadernye

Segmentojadernye

0,4

3,2110,44 29,2111,12

0

3,5110,31

25,81±1,01

0

3,24±0,35

33,0311,14 **

0

2,2310,26*

34,1211,23*

Lymphocytes, % 49,5610,01 51,3210,92 49,01Ю, 06* 48,11Ю, 97*

monotsity, % 6,4110,44 7,5210,32 3,4110,34* 4,3110,22*

The note: the difference between investigated indicators is authentic at: * < 0,01; ** р< 0,02: относительно начало опыта

rmorfologicheskie indicators of blood of sows at application mastometrina

In blood at animals normalisation of morphological structure of blood so has statistically authentically decreased SOE with 11,27±0,74 to 9,37±0,14 mm/ch was observed, the quantity of leucocytes with 17,32±0,95 to 1 1,64yo1,36H109/l, in the leukocytic formula - eosinocytes with 11,84±0,22 to 11,23±0,26 %, palochkojadernyh neutrophils with 3,51 ±0,31 to 2,23±0,26 %, lymphocytes with 51,32+0,92 to 48,11 ±0,97 %, monotsitov with 7,52±0,32 to 4,31 ±0,22 % has decreased, but the maintenance of haemoglobin with 10,33±0,23 to 11,87±0,44 g / %, quantity of erythrocytes with 4,21 ±0,66 to 6,50+0,24X10|2/l, in the leukocytic formula segmentojadernyh neutrophils with 25,81 yo 1,01 to 34,12± 1,23 % (tab. 2.6.1) has statistically authentically increased.

At research of whey of blood of sows it has been established, that in control bunch the quantity of the general the-squirrel, albuminov has statistically doubtfully increased, but the quantity of alpha globulins with 12,86±0,35 to 14,63± 0,17 %, beta - globulins with 15,57±0,05 to 15,85±0,07 % has statistically authentically increased, but decrease in gamma globulins with 22,66 +0,26 to 19,49± 0,12 % (tab. 2.6.2, fig. 2.6.1,2.6.2,2.6.3) was observed.

In skilled bunch of animals, at sows the quantity of alpha globulins has statistically doubtfully increased, but is statistically authentic gamma globulins with 11,32±0,11 to 14,22±0,18 (r

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A source: GRIGORIEV Elena Nikolaevna. MORPHOFUNCTIONAL CHANGES IN THE GENITAL ORGANS AND IMMUNOLOGICAL PARAMETERS OF THE BLOOD OF SOWS IN THE POSTBIRTH PERIOD AND METHODS OF INCREASING THEIR FERTILITY. DISSERTATION on the degree of candidate of veterinary medicine. KOSTROMA - 2004. 2004

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