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THE WORK GENERAL CHARACTERISTIC

Theme urgency. One of the main deterrents in an intensification svinovodstva and increases of efficiency of animals is barrenness which the notable damage causes.

In difference from other agricultural animals the biologically-economic features allowing at rather low expenses of work and means, an economical expenditure of forages (4-6 forages are peculiar to pigs.

A unit on 1 kg of a gain of alive mass) to receive meat production with a high lethal exit (72-85 %). In comparison with indicators traditional svinoferm the organisation industrial svinokompleksov allows to save on 20-30 % expenses of forages for a unit of production and more than in 4 times to raise labour productivity. (Sergienko A.I., 1991).

Postnatal diseases of pigs cause a notable economic damage. In frame nozologicheskih forms of these diseases a syndrome metrit - a mastitis-agalaktija (MMA) and sharp postnatal endometrit, are one of barrenness principal causes that leads to decrease in efficiency, premature vybrakovke animals and  destruction of neonatal pigs.

For preventive maintenance and treatment endometrita various chemotherapeutic means are offered, the long which season of use has caused appearances in the nature resistant shtammov pathogenic and is conditional the pathogenic microorganism and allergic responses at animals and the person, has provoked ecological and other unfavorable consequences (Nezhdanov A.G., 1994).

Treatment-and-prophylactic means applied now not always satisfy veterinary requirements on effecting that leads to necessity of research of highly effective, rather cheap and technological medical products for application (Nazarov

M. V with soavt., 1999; Podugolnikova E.G., 2002; Punks B.G., 2003; Griga E.N., 2003; Chuchalin S.F., 2004; Hozhenaev J.K., 2004; Raragiannidis A.ct. all., 1999; Brooks J., 2001).

Now, gomotoksikologija as one of homoeopathy directions, is used not only in medicine, but also has received a wide circulation in veterinary science (Lipin A.V., 2002; the Sokolov of Century D, etc., 2003; Komisarsnko A.A., etc., 2003; Oak. L, Ulko N.V., 2003; Olenov A.L., 2003; Gavrilov J.V., etc., 2003; Panferov O. V, 2004; Botchkarev V. N, 2004; Fedotova N.A., 2004; Rogers A, 1992; Lokken R, 1995).

Feature of homoeopathic remedies is not only their cheapness and good enough therapeutic efficacyy, but also absence of residual quantities of medical products in meat.

Therefore, revealing of new effective remedies of preventive maintenance and treatment of postnatal complications at the pigs who are not influencing an ecological situation, in the form of collateral action on an organism of animals and the person, is one of paramount problems of a veterinary science and practice.

The purpose and research problems. The purpose of the present work was studying of influence of postnatal complications on morfofunktsionalnye, biochemical, immune processes in an organism of pigs in the conditions of industrial complexes, and also working out of the scientifically-proved actions for preventive maintenance of infringements of reproductive function at sows.

For achievement of this purpose following problems have been put:

1. To study a state morfofunktsionalnogo the status, biochemical, immunologicheskih processes at normal and pathological flow of reproductive processes;

2. To establish influence antioksidantnogo and homoeopathic preparations on indicators of the general natural resistance, morphological functions and flow postnatal involjutsionnyh processes in generative organs at sows after sorts;

3.

To fulfil a new method of correction of begetting power of sows at application of a homoeopathic preparation "Mastometrin" and to define economic efficiency of spent actions.

Scientific novelty. For the first time indicators of reproductive function and degree of diffusion of akushersko-gynecologic diseases at sows on complexes of the Yaroslavl and Kostroma ranges are studied, and also the economic damage from barrenness is defined.

On the basis of complex clinical, hematological, biochemical, morphological and immunologicheskih researches adaptable possibilities in an organism of sows in a pathogeny of postnatal diseases for the first time are studied.

The biological potency antioksidantnogo a preparation "Emitsidin" and a homoeopathic preparation "Mastometrin" is experimentally proved, their ability to influence the morphological, biochemical and immune status of sows in a puerperal period is defined. '

The theoretical and economic substantiation is given the scheme of preventive actions of postnatal complications at the sows developed on the basis of application of a homoeopathic preparation "Mastometrin".

The theoretical and practical importance. On the basis of complex researches of the clinical, hematological, biochemical and immune status of sows ecologically pure and effective mean of treatment and preventive maintenance of postnatal complications with use antioksidantnogo and homoeopathic preparations is offered effecting.

Rational schemes of use "Emitsidina" after sorts and "Mastometrina" - for preventive maintenance and treatment of postnatal complications at sows are offered.

Introductions of results of researches. Results of researches are introduced on a pig-breeding complex of Joint-Stock Company "Levashov" of the Yaroslavl range that is noted in the adoption deed of research work from January, 5th, 2004 confirmed in department of veterinary science of department of agrarian and industrial complex, preservation of the environment and wildlife management of the Yaroslavl range.

The received results are used in educational process FGOU VPO «Kostroma GSHA», the St.-Petersburg state academy of veterinary medicine, FGOU VPO «Buryat GSHA of V.R.Filippova», Oryol GAU, Vjatsky state agricultural academy, Orenburg GAU, the Mordovian state university.

The substantive provisions born on protection:

1. Analysis of reproductive feature of sows in the conditions of pig-breeding complexes of the Yaroslavl, Kostroma ranges and degree of diffusion of akushersko-gynecologic diseases;

2. The characteristic clinical, hematological, biochemical and immunologicheskih changes in an organism of sows at normal and pathological flow of reproductive processes;

3. To establish use possibilities mastometrina and emitsidina for correction of adaptable loads on an organism of sows in a puerperal period and at postnatal complications;

4. Recommendations about early diagnostics, complex treatment and preventive maintenance of postnatal complications at sows a homoeopathic preparation mastometrin.

Work approbation. The basic stuffs of the dissertation are reported, discussed and approved on: interuniversity scientifically-practical conference «Actual problems of a science in agrarian and industrial complex» (Kostroma, 2002, 2003, 2004);

Interuniversity scientifically-practical conference (Ivanovo, 2002); the first international conference in St.-Petersburg «Modern questions of veterinary homoeopathy» (S.-Petersburg, on October, 22-23nd 2003); scientifically - practical conference «homoeopathy Application in veterinary science» (Moscow, on January, 23-25rd 2004); scientifically-practical conference «the Theory and practice of veterinary homoeopathy and akupunktury» (Moscow, on October, 2-3nd 2004); at intercathedral session of faculty of veterinary medicine and zootehnii Kostroma GSHA (2004).

Publications. On a dissertation theme 11 scientific works are published. Volume and dissertation frame. The dissertation is stated on 160

Pages of the computer text also consists of introduction, the review of the literature, own researches, discussion of the received results, conclusions and offers for effecting. Work includes 29 tables. 45 drawings, 214 sources of the literature, including 65 foreign authors.

1.

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A source: GRIGORIEV Elena Nikolaevna. MORPHOFUNCTIONAL CHANGES IN THE GENITAL ORGANS AND IMMUNOLOGICAL PARAMETERS OF THE BLOOD OF SOWS IN THE POSTBIRTH PERIOD AND METHODS OF INCREASING THEIR FERTILITY. DISSERTATION on the degree of candidate of veterinary medicine. KOSTROMA - 2004. 2004

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